This gene here is really a member in the SUMO gene relatives. This family of genes encode compact ubiquitin-related modifiers which are hooked up to proteins and Regulate the focus on proteins' subcellular localization, steadiness, or activity. The protein described With this record is found during the cytoplasm and particularly modifies IKBA, resulting in negative regulation of NF-kappa-B-dependent transcription of your IL12B gene.
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